About 1 result found for searched term "Avapritinib (BLU-285)" (0.195 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6202 | Avapritinib (BLU-285) | VEGFR/PDGFR |
| Avapritinib | ||
| Avapritinib (BLU-285) is a small molecule kinase inhibitor that potently inhibits PDGFRα D842V mutant activity in vitro (IC50 = 0.5 nM) and PDGFRα D842V autophosphorylation in the cellular setting (IC50 = 30 nM); also a potent inhibitor of the analogous KIT mutation, D816V in KIT Exon 17 (IC50 = 0.5 nM). | ||
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